Question

18.2.10. Diffusion of Uric Acid in Protein Solution and Binding. Uric acid (A) at 37°C is diffusing in an aqueous solution of proteins (P) containing 8.2 g protein/100 mL solution. Uric acid binds to the proteins, and over the range of concentrations pres- ent, 10 g mol of acid binds to the proteins for every 3.0 g mol of total acid present

Instructions:

1) Add a drawing to schematically show blockage in part (a).

2) Add a drawing to schematically show blockage and binding in part (b).

3) Add a schematic in part (c).

Answer 1

Solution;

Given that;

solution- we know given values is temperatura, 37°C at unic Acid (A). Dp = 0.09l xos (m²/s DAB = 1.21x10-4 cmids igmol of acid binds to proteins for every 3.0 g mol q total acid present in the solution 'Assume no binding . . DAP = DAS (1-1.81x1ó?<p) (p = 8.29 x 1kg xime loome looog 100 m² = 82kglms DAP DAB = R -181x10²x82 0.852

J Here Assume blockage plus binding effects predict the ratio DAP : mm m m DAB fore | DAP - PA3 ( - J. 81 x 16°C) 7. op (y. bourda) 7 Igmo acid binds to the protein tor Egmol acid. DO 100 fre / 34.33 ID D = 1. 21 x10 °Co gs: (84 8 )+ 0-0 O P = 6 -7|12 x C */ 100 Given. The unic acid at 37c it is diffusing in an aquour solution of protiens (P) containing 8.2g Protein I 100 ml solution

Here Flux , NA = Dap C Caracan) Zz-ZI CAI=0.05g/ O CA2= og Z2-Zi=1.5. , um= 1.58 104cm. NA = 0.7112x10 s co.os-o) 1.5X104. x1000 NA - 2.391 x10 glemts, Thank you