Question

6&8

OH A. Place a on cach chiral enters in compounds above. B. Draw a Fisher projection of A and label it C. Draw all possible dinstereomers of A. D. How many total stereoisomers are possible for A (including All Label any meso compounds that you have drawn or were drawn for you Select the term that best describes the relationship between the following structure drawings: A identical C. diasteroomers B. enantiomers SCH CH.CH OCH Kajan BE H ISH, HCY CH, OH 8. Draw stereochemical drawings of the product(s) of cach of the following reactions (use the wedge dash drawings provided). In the provided circles, assign configuration R/S for the indicated chiral carbons and determine the stercochemical relationship between the final two products, 2-butyne - NHL, 1. MCPBA 2. H,0,H,O Y | 00 00 Stereochemical drawing of product(s) of 1. MCPBA

Answer 1

QA 1. Na 2- butyne NH3 (1) GFC=C-CH 1. MCPBA 2. H907, M20 Na uful CH-C= C- CH, NH, 4) - CH3 g- butyne Trans addition 11. MCPBA | 2. H30t, H₂O Cl3 -Junga Stereochemical drawing of product of 1. MCPBA

Cu3 * TH HO - (A) (8) Chiral centres marked with (*) in A Fischer projection of A CH3 HOH CH3 (c) Diastereoners : which are not mirror images (C) CH3 H HOH HOT CH3 0 Total no. of stereoisomers : 29 = 2² - 4 (E) due to Meso Compound: Optically in active intemal compensation 3 hot hon H6 O - H osha