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Help with question #4. The reaction can be taken from #1
. wILLIAMSON ETHER SYNTHESS: PREPARAT?ON OF PHENACETN FROM ACETAMINOPHEN LA8 10 LAB 10 ? NAME DATE LAB SECTION Answer the following questions in the pre-lab section of your notebook. 1. Draw the mechanism for the reaction between phenacetin, potassium carbonate, and 2. List three limitations of the Williamson ether synthesis and explain how our choice of 3. What is the purpose of the rotary evaporator? What other technique that we have learned Model: For this question, you will be graded on completion, rather than correctness of the iodoethane. reagents circumvents those limitations. in CHEM 233 this semester is the rotovap replacing? model. Be sure to label your model and describe what each representation means, if necessary. 4. Draw a diagram that models what happens to the nucleophile in your reaction when dis- solved in 1) 2-butanone vs. 2) 2-butanol. Which is the better choice of solvent? Why is this more important for an S,2 reaction than for an S, 1 reaction?
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