Efficacy of a new drug, referred to as Drug 2 is tested over the
already existing drug,referred to as Drug 1, for a particular
disease. The data on the number of people usingDrug 1 and Drug 2
vs. people who are cured or not cured are given in Table 1. Test H0
that there is no difference between Drug 1 and Drug 2 in curing
people, at 5% level of significance. Use
table 1:
| cured | not cured | total | |
| drug 1 | 37 | 13 | 50 |
| drug 2 | 88 | 21 | 109 |
| total | 125 | 34 | 159 |
| Applying chi square test of independence: |
| Expected | Ei=row total*column total/grand total | cured | not cured | Total |
| Drug 1 | 39.310 | 10.692 | 50.00 | |
| Drug 2 | 85.692 | 23.308 | 109.00 | |
| total | 125.00 | 34.00 | 159.00 | |
| chi square χ2 | =(Oi-Ei)2/Ei | cured | not cured | Total |
| Drug 1 | 0.136 | 0.498 | 0.6340 | |
| Drug 2 | 0.062 | 0.229 | 0.2907 | |
| total | 0.1979 | 0.7269 | 0.925 | |
| test statistic X2 = | 0.925 | |||
since test statistic X2 =0.925 <3.84 :
we fail to reject null hypothesis
we do not have sufficient evidence to reject the hypothesis that there is no difference between Drug 1 and Drug 2 in curing people,
Efficacy of a new drug, referred to as Drug 2 is tested over the already existing...
A small study is conducted involving 10 infants to investigate the association between gestational age at birth, measured in weeks, and birth weight, measured in grams.: Cured Not Cured Drug 1 37 13 Drug 2 88 21 Total 125 34 Total 50 109 159 Table 1: Gestational age: 34.7, 36, 29.3, 40.1, 35.9, 40.8, 38.3, 37, 41.2, 39.8. Birth weight: 1895, 2030, 1440, 2835, 3115, 4013, 3174, 3625, 2289, 2845. . Find the correlation coefficient r of the gestational age...
Wilfley and colleagues (2008) tested whether the antiobesity drug sibutramine would be an effective treatment for people with binge eating disorder. They measured the frequency of binge eating every 2 weeks for 24 weeks during treatment. The following table lists a portion of the data similar to results reported by the authors for the frequency of binge eating over the first 8 weeks of the drug treatment. Frequency of Binge Eating Baseline Week 2 Week 4 Week 6 Week 8....
10 PPH4801/MPHDHM9 Jan/Feb 2016 QUESTION 2 A clinical tral is run to assess the efficacy of a new drug to reduce high blood pressure Patents with a diagnosis of hypertension are recruted to participate in the tnal and randomised to receive ether the new drug or placebo Particpants take the assigned drug for 12 weeks and their blood pressure status is recorded At the end of the tral, participants are classified as stil having hypertension or not The data are...