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Which of the following amino acids is not produced from 3-phosphoglycerate (3-PG), an intermediate of the glycolysis pathway?
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Answer #1

Answer is D (proline)

Glcolysis pathway is the metabolic pathway,which covert glucose into pyruvate and lactate.

Serine,Cysteine, and Glycine are formed from 3-Phosphoglycerate.But,Proline is not formed.Proline is non essential aminoacid,Glutamate is the precursor of proline and arginine.serine is the precursor of glycine and cysteine.Serine is synthesised from 3-phosphoglycerate,an intermediate in glycolisis.Oxidation to 3-phosphohydroxypyruvate is the first step.The  alpha ketoacid transmitted to 3-phosphoserine,then hydrolised to serine.

Serine +tetrahydrofolate \rightarrow glycine + methylenetrahydrofolate +H2O

In glycine formation ,the side chain methyl group transffered to tetrahydrofolate.

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