Question

6. Synthesis prep. The transformations shown below require a series of two subsequent reaction steps to complete. i. Identify the functional groups (FG) in the starting material and the final product. ii. Refer to the "Synthesis Map from the lecture notes. How does the structure change? Which functional group must you pass through to complete the overall transformation? What is the structure of the intermediate product that you must form before the final product? ini. What reagent(s) are needed to convert the starting material to the intermediate product? (Be sure to take stereochemistry into account.) What reagent(s) are needed to convert the intermediate product to the final product? iv. 2 reaction steps SCH FG in Starting Material FG in Intermediate Product FG in Final Product to form intermediate Regents) to form final product: Regents) product: 2 reaction steps FG in Starting Material FG in Intermediate Product FG in Final Product to form intermediate Regents) to form final product Regents) product Gin Starting Material FG in Intermediate Product FG in Final Product form Regents) to form final product Regents) to product

Answer 1

Nasch PO63 lini Cushy elsh Pyridine Seth FG in slashing material FG in intermediate Prodluct FG in final product alcohol (Rom) Thioether alkyl halide (R-Br) R-S-R Reagent to Loom intermediate Procluct PBog Ryridine Reagent to boom final Product che SNG | Chish (6) A meong ome NaH me e meon on me-I TFG in konal Product FG in stashing material eposuide in Frin Enkirmediate Product alcohol fron) ether (R-OR) ether Ro-R & Reagent to loom intermecliate Product Reagent to boom final Producti Nah, mert on Naomel meout

судов FG in final product FG in slashing makríal Ketone (R-G-R) FG in ankstovediate 1 Product alcohol alkene (-C=(-). CR-OH) Reagent to boom Ional Product Reogent to Lorm intermediate Product els-mg Byl too 4soula