Question

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Chapter 11 - Question 1 What is the best reagent to make the following product? Chapter 11 - Question 2 What is the best reagent to make the following product? Chapter 11 - Question 3 What is the best reagent to make the following product? OH Chapter 11 - Question 4 What is the best reagent to make the following product?

Answer 1

-NED 7 1. Birch returtian 838-8- Na Lianha Y – 7 o here the birch vetuctian occurs. o Birch reduction cecurs in any cangugated runtom, ar nancanga cated egntem, which have Lumo lesser energetic than the LUMO of normal ethylene molecule & Cahu) o Due to the langugalian of benzene, the energy of the LUMO is law and is feasible to accept eleekran. o The ratical anian, maintains maximum distance between the unpaire and the lone pair to minimize the repulsiaus. • The single c is fanated by Na, and the single e- is the mont efficient nucleottile in the universe. Nalliq MHZ har NB Slechy 1 M-Br Br Br-Br + Br-Br. + Bri Bror J o The NBS (N-Bromo Succinimide) cantains HBr as the impurity, to some extent. o The Brw attacks NBS to Parem the Brain the medium, and that reacts in the ratical mechanism, to occur brominarian. • The, benzilie pposition is favoured, as the ratical farmed will be stabilised by cangugarian.

OH - ì) N B slecly i, OH YN CWOH 11) 03/H20 Attack Bavaweet at benzilie position. Stepal + P or Brio Il t Br-Br nohu el é Er + Br - Bri Broz v 2v Step-2 E-2 NaOH OHTE o The E-2 eliminatian occurs by the antiperiplanar arrange ment of the eliminating greaup. O E-2 Represents the and arter Kinetics at the mechanism As two reactants countrols the rar. Step-7-02onolysis - ShOH + HCOOH Ph Ph- T 03/H10 (न LA + I=Otro CHEF old T - Ph H Phytni ar o Ou Ache _PA ñ ozonide HoH V HO Cola Pho + CH = 0 + H2O2 1 co] oxidation by H2O2 Phymol + Ehted HCOOH

O Here the oz is a deipolar molecule and it ean a and acceptar. ale and it can act as both danar o Furnt the mola a keto anda Zwitteriou ogf different substitutians ana armed then, it decampanes to chthen reacts to farm ozonides. as an alkane wauld have bechthere, hat cauld have given, dubbercut neales ozov Exom A Agorát XºXA ♡ B ot BX XB to do Blo o The Hoo gets onitinct to H2O, and it oxiduse to acid- and it oxidases the aldchytes, @4 nebo Hel better o Here the Ht attacks the termin attacks the terminal e-alan, so that marentable benzilie cartocalian will Farm, which is stabilised by eangagatan oge benzilic pasition would net have bechartacked, then the terminal carbocalian was not possible to stabilise by cangugan - tian. -> No cangugatian to atabiline. H