Question

draw the catalytic cycle for the formation of 4-phenylphenol via this suzuki reaction. please write out full compounds in the diagram and not just R1,R2, etc. it should include oxative addition, transmetallation, reductive elimination abd regeneration of Pd(0), and rationale for the quantity of base used.

он 10% Pd/с K.CO3, H,0 ОН

Answer 1

1) oxidative addition happens in first step which changes the ocidation number of Pd.

Pd(elle Pa REGENARATION oxidative addition REDUCTIVE ELIMINATION TRANSMETALLATION. o Lacakt To BlOH)2 + KalO3

Then transmetallation step occurs where phenyl group is handed over to Pd by Boron.

Then reductive elimination occurs to give product