Question

11. (S)-isobutylphenylpropionic acid was synthesized utilizing an enzymatic reduction. This reaction however yielded both the R and the S version of this compound. When the species were analyzed they gave an optical rotation of +12.5°. The concentration and path length used were 0.5g/mL and 1.Odm. Given that in order for this compound to be pure the literature rotation was +36º what is the enantiomeric excess? And how much of the S compound is in solution? 1. 69% and 84.5% 2. 46% and 73% 3. 78% and 89% 4. 55% and 77.5%

Answer 1

LE +12.50 x0.5=25° Specific gotanon [2], - Obs. oofabon - 712.5 loc Formula of enantiomeoic excess, ee Spigotabon - X100 gotanion of pure enantiomes = 25*100 36 ee = 69.).] %. of Senann'omos = 5 +50 = 69 + 50 = 184.5):