Question

Hello as a replacement to actual labs for my orgo 2 lab with coronavirus, I have been given worksheets of experiments and expected to figure it out with no sort of instruction. gotta love online orgo labs which i am not adjusting well to.

can someone be kind enough to please go question by question and explain each one to me in detail so I can actually understand what is going on. my professor hasn't even talked about this in lecture yet unfortunately. and im running short on time. this worksheet is due Monday.? I was doing fine in my orgo lab until thos coranvirus bs hit.

3-hydroxybutyric acid methyl ester What starting materials i solvents & reagents are needed to form the above Andalt? What other products m are formed? 12- What is the mechanm for the reaction and formation of the Pastuch 3-hydroxybutyric acid methel ester?

Answer 1

acid methyl estes. 3- Hydrony - butyric OH CH3 -CI \CH2 locH3 애 Aldol condensation. CH3 - -CH2-4 CH3 - H + CH3 CH3 - H CH3 - C - H20/00/ naocl H2O ОН 애 (Hoch- & ocks, Ho 170 459-n" -oh HCG - CH2 - OH CH3 -C-(H7 - COCH 3 CH3-olt + t2o side product other product - G-CH₂-C-H H C - CH3 + CH3 - CH3 – CH 0 z 176 CH3 - G-CH2-C-OctB CH3 - CH2 - CH3-olt ct 3 CH3

3-Hyhony - butyoic acid methyl ester. OH \CH 21 locH3 ② - Mechanism of reaction St-Formcetich of carbania (HB&C Poll cls_E-CH2 5-7 - Nudeophilic attack. O _ IH CHE-c-CH3 OH O CH3-G-CH2-CH3 CH3 420/00 | Naoch 애 CH3 - C-CH2-C TOH Pit C CH3 - C-clt2- c-OH CH₂-OH It OCH 3 CH CH3 - G-CH2-C-OCH 3 I B-IR Spectra - Signal cet about 3300 cm to 3600 cm' due to OH Stretch. signd cet about 1740 cm' due to - c_ Stretch Signal at about 2000 cm' due to sp3 col Stretch. sianal al abes 1450 cm² dee to call bending.. o about 1000 cmt to 1250 cm dueto c-o stretch signal al about 2800 cm? due to -CH2- stretch al abous 1000 signal

methyl ester 3-Hshony - butyric acid OH (C) la) CH3 -CH (d) (b) CH2 HNMR spectra Octa reg a = 8= 1.2 ppm, doublet, 3H b =) s=4.0 ppm , multiplet, lt (-) 6 = 10ppm to 5.oppo, singles, lt d = 8= 2.5ppm , doubled, 2H e = 3.5 ppm , single, 3H.