Question

asses I Mail - kathleen_furt.. Facebook + Drag and drop your images or Click to grosse Q6 (6 points) 6) Indicate how the following compound could be synthesized using a Robinson annulation and provide a detailed mechanism for its synthesis. 00 SU o cks browser - 220100 D1 D100P 1155 0100 154 0100 Cal Q7 (4 points) pe - a 4») ENG 7) Identify the compounds A to D in the following reaction scheme. No need to provide the reaction mechanism for any of the steps. Crowdemark - Goog... Type here to search

Answer 1

Solution Robinson annulation is Micheal addition of cyclohexanones to mettryl vinyl ketone followed by intramolecular abdol condensation to afford six-membered , ß- unsaturated Kelones. For the required roduct , we need two reagents (I) = lyclohexanone. (II) — methyl vinyl kelone MeoNa NOON (I) (II) Required product Following is the detailed mechanism : Step 1 : Enolate formation by the attack of a bale -Meon CH (11) Meo Step_2; Micheal addition {1,4-addition) of (a) and (III) (T) Scanned with CamScanner (IV)

Step 3 : Isomerization of (IV) takes place l as hansisation are Step 4: Alcol condensation takes place in the presence of base Aldol condensation HTB - HOH - step 5: Dehydration of (II) to give the final product. Required Product . Scanned with CamScanner