


4. Synthesis Reactions. Draw the feature product of the following reactions. (8 x 3 pts) 1....
4. Synthesis Reactions. Draw the feature product of the following reactions. (8 x 3 pts) 1. Mg Ph Br 2. CO2 3. H a "NH2 Ph 1. NaOH, CI 2. LAIH b. CHỊCH NHA NaBHgCN, H+ Ph C. Br (excess) NH d NaOH H HO OH H CH e. 1. NaOH H2O NH 2. H+ o= 1. NaOH H2O 2. SOCI N(CH3)2 3 HO
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4. Predict the products for the following reaction sequences. Он sOc/2 1. LIAIH 2. Hо (CH3)2NH (a) pyridine CH3Br base (-HBr) CH3CH2Br base (-HBr) (b) NH2 Br NaN3 (a) LIAIH (c) (b) Н-О MCРВА NaN3 (a) LIAIH4 (d) oH(a) NH2 NaBH3CN (e) H2SO4 5. Predict the major product for the following reactions. 1. excess CH3 NH2 (a) 2. Ag O, H2O heat 1. excess CH (b) 2. Ag20, H2O...
40. (38) Predict the product or provide reagents needed to complete each transformation. OH A (a-b) K-OH excess OH Na+ HCO3-. (c-d) 1. SOCI 2. NH, OH 1. KOH 2. CH3CH2CH Br a H (e-f) NH 3. NHỊNH H, Hz. Pd ?? ?? (g-h) N3 NH2 NOZ (g-k) -NEN OH CI N 1. CH3 2. Ag20 3. heat 1. CHE 2. Ag20 3. heat (l-m) NH2 ?? NEN OH ?? (n-0) CI CI CI CI (put) 1. Mg, ether 2.Co,...
40. (38) Predict the product or provide reagents needed to complete each transformation. OH (a-b) K+-OH excess OH OF 1. SOCI Na+ HCO3- (c-d) 2. NH3 OH 1. KOH 2. CH CH CH Br ol (e-t) NH 3. NHANH H, H2, Pd ?? ?? (g-h) 'Ng NH2 NO2 (g-k) NEN OH 1. CH3 2. Ag20 3. heat 1. CH 2. Ag2O 3. heat (I-m) NH2 OH ?? NEN ?? (n-O) CI CI CI 1. Mg, ether 2. CO2 CH3CH2NH2, H+...
1. Predict the major produc t for the following reactions. (1) CO2 (2) Ho MgBr H,O SOCI CEN dine Cl OH excess NH Ci (CH3)2CuLi Cl (1 excess CH CH2MgBr Ci (2)H20 SOCI NH2 SOCI OH
8. Predict the major product for the reactions below. (4 pts each) "NH2 H*, -H2O NH H*, -H20 i PhD-CH. Ph P=CH2 www Ph = CH.COM CH,CO,H
4. Predict the major product of the following reactions. CHA excess NaOH excess Br2 1.excess NaOH TBSON excess Bra 2. H30+, dilute, cold 3. SOCI py 4, HN OCH3 H3CO 1. Bry_ OH 2. NaSCH2CH3 LIN =LDA, THF, -78°C 1. 2. To 3. Og 4.H2O2, NaOH, H2O 5. OH, DCC
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1. Show the expected product(s) of the following reactions. For products containin or cis/trar asymmetric carbon atoms, indicate relative stereochemistry (syn/anti relationships) and/or whether a racemic mixture is produced. (8 pts each) 1. HNO3, H2so4 NO 2. Fe, HCI OCH3 3. NaNO2 aq. HCI 4, CuCN, Δ сно но 1. Br2 H20 2. Fe SO)S b. HO- -H OH s CH2OH 1. SOCI2 2. NH3 H3C 3. Br2 NaOH, H2O 1. KOH 2. PhCH2CH Br 3. NH2NH2 d....
Which one of the following series of reactions does not produce
a primary amine?
Which one of the following series of reactions does not produce a primary amine? O 1) LiAIH4 (excess) 1) Fe, HCl, H20 NaOH, H2O, heat A) PhCN B) PHNO2 C) PhNHCCH 2) H20 2) NaOH, H2O H2, Raney-Ni O E) PUNHCCH3 1) LIAIH4 (excess) D) PhCH=NH 2) H20 Which of the following amines cannot be made by reduction of a nitrile? Ph2CHNH2 EtNH2 (CH3)2CHCH2NH2 Me3CCH2NH2 A...
10. Which of the following reactions will produce (S)-1-phenylethylamine in high enantiomeric purity as the major product? Check all that apply. Br NK -. NH3 1. pH 5, NaCNBH3 2. NH NH2, heat =: 1. NaCN iv Br 2. LiAIH4, ether 3. H2O OTS 1. NaNz 2. LIAIH4, ether 3. H2O (Ts= para-toluenesulfonyl)