CH3 P, Br2 thern H20 ?? n) CH3 heat then H20 H2N-NH2, KOH, heat 0) n-BuLi...
1. Predict the product(s) for each of the following reactions: H2SO4 NH2 a. 0 1. H2N-NH2, H2S04, -H20 H 2. KOH/H2O b. MeOH, TsOH он H2O C. H2SO4, -H20 HO d. H2O, H30+ e. H20,H30+ 2. Predict the product and draw the full pushing arrow mechanism for the following reaction NH2 H20,H30+ a. b. 3. Devise an efficient synthesis for the following transformation. HO Br Br
Draw the major product for each reaction. он. CH3 heat N(CH3)3 a. LiAIH4, Et20 b. H30*/H20 1. NaCN, DMSO Br 2. a. LiAIH4. THF b. H3O+/H2O 1. NaN3, DMSO Br 2. a. LiAIH4, THF b. H3O /H20 1. HNO3, H2SO4 2. SnCl2 3. Br2 4. a. HNO2, H2SO4 H3C b. H2PO2 NH2 1. NaNO2, HCI, H20 но 2. HBF4
Question 3a) CH3 Br н,С. CH3 H Ph3P CH3 H n-Buli What is the name of the reaction above? 1 point Your answer Which of the following compounds is an intermediate in the reaction above? 1 point CH Ph Ph CH, OⓇ CH3 HCH₂ HC y PhPa HEC Ph-P-0 Ph CH₂ Ph-P-0 Phạ% CHỊ Ph Phen Phon A B с D Ο Α OB
Page 4 CH3 (O CH3CNH но + 2 H20 CH3O 0% NaOH 0 CH3 0 CH CHCH -NH2+H20 KOH H2S04 CHSCH-СОН CH3 (m) + CH O CH3 +HC
g. Ph-C(O)-NH2 4 NaOH Br2 h. (HC)2CH-C(CHa)2 -> HO N(CH3)3 i. Ph-N2, CI- + CuCN --> H30* (cat) Na/ETOH j. cyclohexanone+ H2NOH Pd(OAc)2 (1 mole%) k. Ph-I + 4-O2N-C&H4-HC=CH2 Cul/Pd(PPH3)4) L. HO-CH2-CH2-CC-H +1-CH=CH-(CH2)4-CH3
OH 1) CH3CH2CH2MĚC 2) H2O 1 2. 1) CH3CH2CH2Br 2) P(Ph)3, n-BuLi (You may start with ylide) 3. 4. N [H2SO4 Me2NH -H20 5. m
OH 1) CH3CH2CH2MĚC 2) H2O 1 2. 1) CH3CH2CH2Br 2) P(Ph)3, n-BuLi (You may start with ylide) 3. 4. N [H2SO4 Me2NH -H20 5. m
3) Draw the products of the following hydrolysis reactions. (A) Heat CH3CH2-CH-C-NH-CH3 + HCl + H20 (B) CH, CH, CH, CẠNH CHI Heat + NaOH CH2CH, Heat + HCl + H20 - (D) | " , , wa wo wa – Heat CH3-C-NH2 + HCl + H20 - Heat CH3-C-NH2 + NaOH
2. Predict the product. CH,CH NH2 NH 1. LiAlH 2. H20 Br H30 KOH 1. excess CH1 2. Ag20, H20 heat
1) KOH H, H20 olin Heat 2) Ph-CH2-Br
ZI 5-0 2. Estimate the pl value of the following pentapeptide. Explain. (5 marks) H2N-CHC N-CHC N-CHC-OH CH2 CH3 CHOH CHCH3 CH3 CH3 CH2 CH₂ CH2 NH2