Question

In this experiment, we characterize the products only by obtaining an experimental melting point. How could you use TLC to confirm that (i) your isolated product is pure, and (ii) your product is acetaminophen? [2 marks]

The reaction was: 4-aminophenol + acetic anhydride + water (solvent) --> acetaminophen + acetic acid

Answer 1

Realtion 6 te Holo Но у Acetic NH₂ 4-aminophenol Anhydride Using The we can make here a TLC using the isolated Compound & 6 4-aminophenol & @ Pure aret aminophen (if available) Case-A The Prodret is pure and it is acetaminophine. after Appearance of one spor L Å å & means there is no other impurity Case-B. running The There is un reacted Starting material ® along with product. |- Ã B e A B e Product (crude) 4-aminophmol Pure autaminophin Case-c Completely impure reaction mixture. There are many spote. So suveral polt mixtures, there is is pure only Ar. If in the your product sporu To prove whether your product is autamino. pun, we can compare the The Ppot of yous Compound and separately taken pute" are tamino phon. If they match then your Compound is pure autaminophen.

Apart from can point The also your compare the experimental isolated batch of est literature data of the sure that your compe om you melting autaminophen match then you has high purity of and are its also