Question

Identify the compound C8H9NO2 from its 1H, 13C/DEPT, COSY, HMQC, and INADEQUATE spectra and show all correlations.

'H NMR 600 MHz 5480 5470 Hz 5200 5190 Hz 4910 4900 Hz 4370 4360 Hz 2590 2580 Hz 790 780 Hz 9.0 8.5 8.0 7.5 7.0 6.5 6.0 5.5 5.0 4.5 4.0 3.5 3.0 2.5 2.0 ppm

Answer 1

Based on the provided 1H and 13C NMR experiments (1H-COSY, 1H-13C-HMQC and 13C-13C-Inadequate experiments, the structure of an unknown is proposed as ethyl nicotinate. The details have been explained as below.

V6 The stouture pozded fro unknoon as below to i 2 MF-collano G193 1 mW-151 Name: ethyl nicotmate "UN NR inppm) e- 9.2 (dd in ASH HE J - 2H2), 8.6 (td, 1H, Ard H8, I meta= 242, Jostho - 842) 8.2 (td, 1H AH H10, Imeta= 242, Totho = 8H2), 7.3 (dd, in Ar-H, Ha, Jostho = 8Hz), 4.4(9. 2H, Ochel, H2) 0.get, 34, ocheH3, H1). 930R (din ppm): 166 G6- czo, cy), 152(CH , C3) 150 CCH G6). 137 CCH, C6), 1266¢- , C5), 122(CH CQ) 1611042, 2), 14 (CH3, C1) The 20 HOSY, 'H-13C-HMQC and 13C- 13C Inadequate experiments also show the confirmation & the assigned peaks for protons and rabons of ethyl nicotinate.