which citric acid cycle intermediates are able to cross the inner mitochondrial membrane?
Homework Answers
The citric acid cycle intermediates that can cross the inner mitochondrial membrane are :
a) Citrate : As acetyl Coenzyme A cannot cross the inner mitochondrial membrane and to obtain cytosolic acetyl CoA citrate from the citric acid cycle is carried through the inner mitochondrial membrane into the cytosol.
b) Malate - this crosses the inner mitochondrial membrane where malate undergo oxidation and regenerate oxaloacetate. Thus malate-aspartate pathway takes place.
c) alpha ketoglutarate : These can cross the inner mitochondrial membrane and undergo reverse transamination to form oxaloacetate and glutamate are regenerated through aspartate-glutamate shuttle in order to continue the citric acid cycle in the cytosol.
d) Fumarate, succinate and malate : Dicarboxylate carrier helps in transport of these molecules across the inner mitochondrial membrane from mitochondria in exchange with the inorganic phosphate
whereas tricarboxylate carrier helps in transport of citrate, isocitrate, alpha ketoglutarate and hydrogen ions in exchange for malate.
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which citric acid cycle intermediates are able to cross the inner
mitochondrial membrane?
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Problem 14.21 - Enhanced - with Solution 19 of 19 Assuming a membrane potential across the inner ...
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3. The energy difference for protons across the inner mitochondrial membrane is given by: AG 2.30...
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Complete the sentences to explain why long chain fatty
acids cannot pass the mitochondrial membrane via diffusion, and the
mechanism by which the cells transport them.
duction of Energy via Fatty Acid Oxidation CPT II mitochondrial matrix large CPT I inner mitochondrial Long-chain fatty acids have an alkyl chain of more than 10 carbon atoms. Fatty acids with alkyl chains of this length are characterized as size. This length decreases their ability to cross the lipid bilayer of the mitochondrial...
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3. The energy difference for protons across the inner mitochondrial membrane is given by: AG 2.303RT x log Hout + 2A Hin How would this equation be modified by the following conditions? a. If protons were uncharged species b. If the inner mitochondrial membrane was freely permeable to ions other than protons. c. If the equation was written as a function of pH.
3. The energy difference for protons across the inner mitochondrial membrane is given by: AG 2.303RT x...
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