For urine drug testing, which method is better? GC-MS vs LC-MS?
For urine drug testing, which method is better?
GC-MS vs LC-MS?
Homework Answers
GC-MS is better for urine drug testing. In GC-MS mobile phase is inert gas but for LC-MS mobile phase is a liquid. GC is used for analysing volatile organic sample and LC is used for polar molecules.
In cohesive sentences explain the difference between SIM versus SRM in LC-MS and GC-MS.
In cohesive sentences explain the difference between SIM versus SRM in LC-MS and GC-MS.
Why are metabolic pathways important for urine drug testing? Discuss the reason for drug interaction and...
Why are metabolic pathways important for urine drug testing? Discuss the reason for drug interaction and mixtures with opioids in relation to fatalities.
Pyrene was analyzed using GC-MS at the selected ion mode. The calibration curve of peak area (GC-MS response) vs. concentration is shown below along with the regression output. A blank sample was ana...
Pyrene was analyzed using GC-MS at the selected ion mode. The calibration curve of peak area (GC-MS response) vs. concentration is shown below along with the regression output. A blank sample was analyzed seven times, giving a mean peak area of 125 and standard deviation of 15. A check standard at 0.5 ppm was also measured seven times, giving a standard deviation of 300. The raw data, Excel's printouts of linear regression along with the line plot are attached. (a)...
What are the significant factors in choosing the Right LC-MS Method / Instrument for a Given...
What are the significant factors in choosing the Right LC-MS Method / Instrument for a Given Type of Samples
Could we have used Mass Spectrometry after the GC analysis (GC-MS) to identify which peak on...
Could we have used Mass Spectrometry after the GC analysis (GC-MS) to identify which peak on the GC was which isomer? Why or why not?
The confirmatory method of identifying illegal drugs is GC-MS. The suspected drug is analyzed and...
The confirmatory method of identifying illegal drugs is GC-MS.
The suspected drug is analyzed and its spectrum is compared to a
library of spectra. Using the following spectra, is it possible to
identify the evidence sample? Justify either a positive or negative
finding.
Evidence 100 80 60 40 20 0 0 50 100 150 200 250 300 350 400 w/s Morphine 100 80 e0 40 20 LSD 100 80 S 40 3 20 д 50 100 150 200 250 300...
18. The method detection limit for GC/MS analysis of atrazine is typically near 0.010 ppb while...
18. The method detection limit for GC/MS analysis of atrazine is typically near 0.010 ppb while the ELISA test describes its sensitivity as the “least detectable dose” (LLD) of 0.05 ppb of atrazine in water. Based on this comparison one would think that the ELISA test is suitable for monitoring part per billion levels of atrazine in surface water. In the example above, can you think of some reasons (at least 2) why the results are not identical? Does each...
Which of the following is a major advantage of using immunoassay for drug screening? 1. A....
Which of the following is a major advantage of using immunoassay for drug screening? 1. A. Specificity Sensitivity B. C. Speed D. Standardization Which of the following is a majer advantage of using mass spectrometry for drug testing? 2. Specificity A. B. Sensitivity C. Speed D. Standardization A patient's urine tested positive for temazepam, diazepam, nordiazepam, and exazepam by mass spectrommetry, which is the most likely drug the patient is using? A. Diazepam Nordiazepam B. C. Охагерат D. Temazepam
1. Which method of GC gives the highest number of theoretical plates and hence the best resolutio...
1. Which method of GC gives the highest number of theoretical plates and hence the best resolution/separating power? a. Open tubular GC b. Packed Column GC 2. What is the most appropriate detector for the following analytes? "Electron Capture", "Thermal Conductivity", "Thermionic" - Halogenated Compounds "Electron Capture", "Thermal Conductivity", "Thermionic" - Phosphorous and Nitrogen compounds "Electron Capture", "Thermal Conductivity", "Thermionic" - Mixture of gases.
Chapter 9, Section 9.4, Question 013 The rate at which a drug leaves the bloodstream and passes into the urine is proportional to the quantity of the drug in the blood at that time. If an initial dos...
Chapter 9, Section 9.4, Question 013 The rate at which a drug leaves the bloodstream and passes into the urine is proportional to the quantity of the drug in the blood at that time. If an initial dose of Qo is injected directly into the blood, 27% is left in the blood after 4 hours. (a) Write and solve a differential equation for the quantity, Q. of the drug in the blood after t hours. Use k as the positive...
Pyrene was analyzed using GC-MS at the selected ion mode. The calibration curve of peak area (GC-MS response) vs. concentration is shown below along with the regression output. A blank sample was analyzed seven times, giving a mean peak area of 125 and standard deviation of 15. A check standard at 0.5 ppm was also measured seven times, giving a standard deviation of 300. The raw data, Excel's printouts of linear regression along with the line plot are attached. (a)...
The confirmatory method of identifying illegal drugs is GC-MS.
The suspected drug is analyzed and its spectrum is compared to a
library of spectra. Using the following spectra, is it possible to
identify the evidence sample? Justify either a positive or negative
finding.
Evidence 100 80 60 40 20 0 0 50 100 150 200 250 300 350 400 w/s Morphine 100 80 e0 40 20 LSD 100 80 S 40 3 20 д 50 100 150 200 250 300...
Which of the following is a major advantage of using immunoassay for drug screening? 1. A. Specificity Sensitivity B. C. Speed D. Standardization Which of the following is a majer advantage of using mass spectrometry for drug testing? 2. Specificity A. B. Sensitivity C. Speed D. Standardization A patient's urine tested positive for temazepam, diazepam, nordiazepam, and exazepam by mass spectrommetry, which is the most likely drug the patient is using? A. Diazepam Nordiazepam B. C. Охагерат D. Temazepam
Chapter 9, Section 9.4, Question 013 The rate at which a drug leaves the bloodstream and passes into the urine is proportional to the quantity of the drug in the blood at that time. If an initial dose of Qo is injected directly into the blood, 27% is left in the blood after 4 hours. (a) Write and solve a differential equation for the quantity, Q. of the drug in the blood after t hours. Use k as the positive...
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