1. Blood is maintained at a pH of 7.4 by the primary buffers in the plasma...
1. Blood is maintained at a pH of 7.4 by the primary buffers in the plasma and secondary buffers in the erythrocytes. The plasma contains carbonic acid/bicarbonate as one of its primary buffers. The pK for this buffer system is 6.3
H2CO3 <=> H+ + HCO3-
What is the ratio of bicarbonate to carbonic acid in normal blood plasma?
Homework Answers
Solution:
According to Hendersen-Hasselbalch equation for buffer solution,
pH = pKa + log [salt] / [Acid]
For bicarbonate ( HCO3-) and carbonic acid (H2CO3) buffer above equation becomes as,
pH = pka + log [HCO3-] / [H2CO3]
7.4 = 6.3 + log [HCO3-] / [H2CO3]
log [HCO3-] / [H2CO3] = 7.4 - 6.3 = 1.1
[HCO3-] / [H2CO3] = antilog 1.1 = 12.589 = 12.59
Hence, ratio of bicarbonate to carbonic acid = 12.59
Add Answer to:
1. Blood is maintained at a pH of 7.4 by the primary buffers in
the plasma...
The pH of blood plasma is 7.40. The principal buffer system is HCO3?/H2CO3. Calculate the ratio...
The pH of blood plasma is 7.40. The principal buffer system is HCO3?/H2CO3. Calculate the ratio [HCO3?]/[H2CO3] in blood plasma. (Ka of H2CO3, carbonic acid, is 4.5 × 10?7) Enter your answer in the provided box.
Carbonate buffers are important in regulating the pH of blood at 7.40. If the carbonic acid...
Carbonate buffers are important in regulating the pH of blood at 7.40. If the carbonic acid concentration in a sample of blood is 0.0010 M, determine the bicarbonate ion concentration required to buffer the pH of blood at pH = 7.40. H2CO3(aq) = HCO3- (aq) + H+ (aq) Ka, = 4.3 x 10-7 27 Concentration =
8. The normal pH of human blood is about 7.4. The carbonate buffer system in the blood uses the following reaction:...
8. The normal pH of human blood is about 7.4. The carbonate buffer system in the blood uses the following reaction: CO2(+ 2H2O() H2CO3(aq) HCO3(aq) + H:04) The concentration of carbonic acid, H2CO3, is approximately 0.0012M and the concentration of the hydrogen carbonate ion, HCO3 is around 0.024M. Calculate the pH of blood
Post Lab Activity Acids, Bases, pH, and Buffers 1. Calculate the pH of a 0.08 M NaOH solution. 2. Hydrochloric acid...
Post Lab Activity Acids, Bases, pH, and Buffers 1. Calculate the pH of a 0.08 M NaOH solution. 2. Hydrochloric acid is a strong acid and dissociate almost 100% in aqueous solution. If two drops (0.1 mL) of 1.0 MHCI are added to pure water to make 1.0 L solution. What is the pH of this solution? 3. M. What will be the A dilute solution of hydrochloric acid (HCI) has a concentration of 0.1 pH of this solution? 4....
Buffers are common (and extremely important) in biological systems, including in human body. One of the...
Buffers are common (and extremely important) in biological systems, including in human body. One of the most important biological buffers in human blood is the buffer established between carbonic acid and bicarbonate ion (H2CO3/HCO3–). At 25 oC, H2CO3 has a Ka1 of 4.45x10–7 and a Ka2 of 4.69x10–11. a. Will Ka1 or Ka2 of H2CO3 be instrumental in determining blood pH? Briefly explain your reasoning. b. Let’s pretend that there was an equal ratio of carbonic acid to bicarbonate (note...
2. Blood is buffered using a bicarbonate system primarily to accommodate the formation of CO2 in...
2. Blood is buffered using a bicarbonate system primarily to accommodate the formation of CO2 in the tissues. The overall pK for the reaction below is 6.35: CO2 + H2O H2CO3 H+ + HCO3 During acidosis, treatment can consist of IV administration of NaHC03. If the pH of blood is typically 7.4, and the total concentration of carbonic acid/ bicarb is 0.05M, what is the concentration of conjugate base and acid in blood?
8) The pH of human blood is primarily maintained at 7.4 by A) ATP B) a...
8) The pH of human blood is primarily maintained at 7.4 by A) ATP B) a bicarbonate buffer system. C) carbon dioxide-carbonic acid buffer systems. D) B and C. E) A, B and C. 9) The H+ (or H30+) in cells is the same concentration as that of undissociated water. A) Trure B) False 10) A pharmaceutical company hires a chemist to analyze the purity of the water being used in its drug preparations. If the water is pure, the...
(a) Carbonate buffers are important in regulating the pH of blood at 7.40. what is the...
(a) Carbonate buffers are important in regulating the pH of blood at 7.40. what is the concentration ratio of CO2 (usually written H2CO3) to HCO3-in blood at pH = 7.40? H2CO3(aq)-HCO3-(aq) + H+(aq) Ka = 4.3 × 10-7 [H2CO3] / [HCO3-]- (b) Phosphate buffers are important in regulating the pH of intracellular fluids at pH values generally between 7.1 and 7.2. What is the concentration ratio of H2Po4 to HPO2 in intracellular fluid at pH = 7.15? H2PO4(aq)HPO42(aq)H(aq) Ka =...
Explain the role of buffers in the control of blood pH Question In the digestive process,...
Explain the role of buffers in the control of blood pH Question In the digestive process, acids are introduced to the blood more than bases. The bicarbonate buffer system acts to neutralize pH changes in the blood. The respiratory system is involved in the process to help maintain the levels of carbonic acid in the blood. What compound is exhaled in order to reduce the carbonic acid concentration in the blood? Give the answer as a chemical formula. Do not...
The pH of a bicarbonate-carbonic acid buffer is 6.62. Calculate the ratio of the concentration of...
The pH of a bicarbonate-carbonic acid buffer is 6.62. Calculate the ratio of the concentration of carbonic acid ( H2CO3 ) to that of the bicarbonate ion ( HCO3− ). ( Ka1 of carbonic acid is 4.2 × 10−7. ) [ H2CO3 ]/ [ HCO3− ] =
Carbonate buffers are important in regulating the pH of blood at 7.40. If the carbonic acid concentration in a sample of blood is 0.0010 M, determine the bicarbonate ion concentration required to buffer the pH of blood at pH = 7.40. H2CO3(aq) = HCO3- (aq) + H+ (aq) Ka, = 4.3 x 10-7 27 Concentration =
8. The normal pH of human blood is about 7.4. The carbonate buffer system in the blood uses the following reaction: CO2(+ 2H2O() H2CO3(aq) HCO3(aq) + H:04) The concentration of carbonic acid, H2CO3, is approximately 0.0012M and the concentration of the hydrogen carbonate ion, HCO3 is around 0.024M. Calculate the pH of blood
Post Lab Activity Acids, Bases, pH, and Buffers 1. Calculate the pH of a 0.08 M NaOH solution. 2. Hydrochloric acid is a strong acid and dissociate almost 100% in aqueous solution. If two drops (0.1 mL) of 1.0 MHCI are added to pure water to make 1.0 L solution. What is the pH of this solution? 3. M. What will be the A dilute solution of hydrochloric acid (HCI) has a concentration of 0.1 pH of this solution? 4....
8) The pH of human blood is primarily maintained at 7.4 by A) ATP B) a bicarbonate buffer system. C) carbon dioxide-carbonic acid buffer systems. D) B and C. E) A, B and C. 9) The H+ (or H30+) in cells is the same concentration as that of undissociated water. A) Trure B) False 10) A pharmaceutical company hires a chemist to analyze the purity of the water being used in its drug preparations. If the water is pure, the...
(a) Carbonate buffers are important in regulating the pH of blood at 7.40. what is the concentration ratio of CO2 (usually written H2CO3) to HCO3-in blood at pH = 7.40? H2CO3(aq)-HCO3-(aq) + H+(aq) Ka = 4.3 × 10-7 [H2CO3] / [HCO3-]- (b) Phosphate buffers are important in regulating the pH of intracellular fluids at pH values generally between 7.1 and 7.2. What is the concentration ratio of H2Po4 to HPO2 in intracellular fluid at pH = 7.15? H2PO4(aq)HPO42(aq)H(aq) Ka =...
Explain the role of buffers in the control of blood pH Question In the digestive process, acids are introduced to the blood more than bases. The bicarbonate buffer system acts to neutralize pH changes in the blood. The respiratory system is involved in the process to help maintain the levels of carbonic acid in the blood. What compound is exhaled in order to reduce the carbonic acid concentration in the blood? Give the answer as a chemical formula. Do not...
Most questions answered within 3 hours.
-
Where is the error in this code sequence?
String s1 = "Hello";
String s2 = "ello";...
asked 11 months ago -
Financial data for Joel de Paris, Inc., for last year
follow:
Joel de Paris, Inc.
Balance...
asked 11 months ago -
Consider this reaction:
Al2(SO4)3 (aq)+ BaCl3
(aq) Al2Cl6 (aq)- +
3BaSO4(s) . What is the...
asked 11 months ago -
Suppose that Savneet is considering increasing her
recent random sample from 20 car rentals to 40...
asked 11 months ago -
Trucks arrive at an unloading terminal at an average rate of 120
per hour.
Trucks arrive...
asked 11 months ago -
Why are methanol and ethanol completely soluble in water while
octanol is not very little soluble....
asked 11 months ago -
A facilities manager at a university reads in a research report
that the mean amount of...
asked 11 months ago -
When the CuSO4 is rehydrated by adding water to the anhydrous
compound, is this an endothermic...
asked 11 months ago -
A ray of sunlight is passing from diamond into crown glass; the
angle of incidence is...
asked 11 months ago -
A block of mass 0.249 kg is placed on top of a light, vertical
spring of...
asked 11 months ago -
how do the kidneys compensate in the presences of acidosis
a) trigger hyperventilate
b) reserve acid...
asked 11 months ago -
Question 501 pts
The rental rate of capital to the firm increases. Which of the
following...
asked 11 months ago