Question

Which of these peptides has the highest total number of ionizable groups? A. KFYV B. ERSC...

Which of these peptides has the highest total number of ionizable groups?

A. KFYV

B. ERSC

C. PIMF

explain it further by indicating the total number of ionizable groups for each of the peptides. Thanks!

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Answer #1

Answer: B (ERSC)

Here I have ignored the C- terminal and N- terminal groups which are ionizable and this will be equal to 2 for every peptide (one is NH3+ and the other one is COOH-). I have only counted the ionizable side chains. If you want to consider the ionizable terminal group you can add 2 to the number of ionizable groups that I have calculated below for each of the peptides but the answer will be the same.

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