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If 2-stage testing is performed such that only subjects who are positive for both tests are...

If 2-stage testing is performed such that only subjects who are positive for both tests are considered positive, what is the net impact on sensitivity and specificity? A. Sensitivity and specificity will both increase B. Sensitivity and specificity with both decrease C. Sensitivity will increase and specificity will decrease D. Sensitivity will decrease and specificity will increase

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Answer #1

D. Sensitivity will decrease and specificity will increase

(as doing two time test will reduce tested positive given have disease while increase number of tested negative given not have disease.)

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