Question

How many primordial follicles are there before birth and then at birth, puberty and menopause? What happens to most of the follicles? (50 words or less

Answer 1

Oogenesis begins in the ovary in intrauterine life at 6 -8 week of gestation.

• Maximum number of oocytes are at 5th month of development (20 week of gestation) = 6-7 million (before birth)
• At birth it is around 2 million primary oocytes
• At puberty this number is reduced to 300,000 to 500,000 (of which only 500 are destined to mature during individual lifetime and other undergo atresia)
• Most of the follicles die or undergo atresia

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