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What is isotope dilution liquid chromatography/electrospray ionization tandem mass spectrometry? How can it be used to...

What is isotope dilution liquid chromatography/electrospray ionization tandem mass spectrometry? How can it be used to know the content of cigarettes?

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Isotopes are the compounds have different number of neutrons..

Isotopes dilution liquid chromatography is a method of analysis of chemical substances.. In this method, isotopically analysed substance is added to the testing sample Unlike other methods, here the ratios of analyte and isotope chemical is calculated..

In a gas chromatography analysis, decreasing the uncertainty of results isotopic dilution from 5% to 1%. in mass spectrometry (isotopic dilution mass spectrometry or IDMS), the isotopic ratio is better than 0.25%.

https://en.m.wikipedia.org/wiki/File:Principle_of_isotope_dilution.svg

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