Question

2. Adult-onset diabetes is known to be highly genetically determined. A study was done comparing frequencies of a particular allele in a sample of such diabetics and a sample of non-diabetics. The data are shown in the following table: Diabetic Normal lele Type Bb/bb BB 12 39 49 a) Conduct a binomial test of proportions to determine if the frequency of the Bb/bb allele type differs between diabetics and normals. State the nul and alternative hypotheses of your test and interpret your result. (b) Conduct a Pearson test of homogeneity to determine if the frequency of the Bb/bb allele type differs between diabetics and normals. State the null and alternative hypotheses of your test and interpret your result. (c) Confirm your calculations above by conducting the chi-square test of homogeneity in R using the following code. Hand in all of your code and output. Bb.bb c(12,4) BB <-c (39,49) > chisq.test cbind (Bb.bb, BB), correct-FALSE To learn more about the chísq. test function, type help( chísq. test ) in R.

Answer 1

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