Question

How does the epoxide form in this reaction? Please give a detailed explanation.

02.2e, 2H H20 CYP1A1/CYP1B1 Epoxide-Hydrolase H20 benzo[alpyrene +)benzo[a]pyrene-7,8-epoxide CYP1A1/ CYP1B1 он он H20 он +)benzolalpyrene-7,8-dihydrodiol-9,10-epoxide (-benzo[a]pyrene-7,8-dihydrodicl Metabolism of benzo[alpyrene yielding the carcinogenic benzo[alpyren-7,8-dihydrodiol-9,10- epoxide.

Answer 1

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