Question

1-a part of the coagulation cascade which of the follwoing is responsible for the conversion of fibrinto fibringogen?

A)nitric oxide B)prothrombin C)thrombin D)prostaglandin

2- which of the follwoing medications will work to inactivate thrombin through support of anti-thrombin?

A)Unfractionated Heparin B)Direct-Thrombin inhibitors C)Thrombolytic

3-Thrombocytopenia is?

A)chronically elevated thrombin level B)depressed thrombin level C)chrnoically depressed platelet count D) elevated ACT values

4- How are the majority of complication during cardiac catheteriztion treated?

A)intervention B)pharmacologically C)adjustment of preforming procedure D)complication rate is minimal and dose not require treatment

Answer 1

1. C. Thrombin. Coagulation cascade is process of blood clotting and it has series of steps. Thromin is the factor responsible for conversion of fibrinogen to fibrin.

2. A. Unfractioned Heparin. Unfractioned heparin and low molecular weight heparin inhibit free thrombin by binding to antithrombin forming heparin -thrombin-antithrombin complex and prevent clotting.

3. C. Chronically depressed platelet count. Thrombocytes are platelets and thrombocytopenia are low levels of platelet count.

4. A. Intervention. Patients are selected carefully assessing the risk prior to the procedure. Complications may or may not occur. These are monitored and interventions are done with the start of signs and symptoms of complications.