Question

3) Name all possible amino acids for which this might reasonably be the titration curve. Explain your reasoning. (2 pt) 4- OH-Equlralents

Answer 1

From the curve, we find that the given amino acid has two equivalent point and we know only antral amino acid can show such type of graph. So amino acid with alkyl substituent generally show this type of graph. Example: Glycine & Alanine , leucine, isoleucine valime eetc. .. A details study of isoelectric pont of alanine we will discuss below:

Isoelection point determination of nutral amino acid: Me cont H₂N Alarme pH < 1 ) Acidic pH : H₂ - CH - Cook chiz cation PH) 12) => Basic PH : H₂N-CH- coo CH3 anion At pH = I-P. a ag : H₂ N - CH-coo CH₂ Zwitter in Titration curve Alanine Vs. Nach OH to H₂ N CH-Wol - H₂N CH - Coo CH3 2 twitter CH, in a Cartion sind sollows loh svamo o UN- H₂N-CH- coo- CH3 anion pk 2.34 pk = 9.69 0 5 1 pH pk + pkz 1.5 2 2.5 3.0 egu. ÕH = 6.00