based on the strength of the base and the type of alkyl
halide and the possible products are as follows

-OH 5. For the reactions below: a. (10 pts) Predict all products and circle the major product if more than product...
(10 pts) Predict the major product (including stereochemistry if important) of each of these elimination reactions. Indicate whether E1 or E2. 4. H2о 95°C КОН Br 85°C Br
Predict the major product of the following reactions. These are
Hoffman Elimination Problems
To Predict the major produd of the following reactions. NHO excess CH₂ I Ag2o, ita heat xe heat
5. (10 pts) Predict the major product (including stereochemistry if important) of each of these substitution reactions. Indicate whether Sn1 or Sn2. Сндон 15°C Br Br O CH CHEST CH,CHSH 60°C
4. (6 pts) Predict the major product for the following reactions. Remember to indicate stereochemistry, when appropriate. Unless otherwise noted you may assume that each reagent is available in excess. If no reaction is expected, write NR. 1 H2O OTS NaSH ü Nash DMSO Br QB CH,OH CH3OH
For each reaction: draw all products, label the Zaitsev and
Hofmann products, if there is more than one elimination product,
and circle the major product.
Hint: LDA is a strong bulky base
4. (16 pts) For each reaction: draw all products (use your Substitution/Elimination Review PowerPoint and your book!) label the Zaitsev and Hofmann products, if there is more than one elimination product. circle the major product. Hint: LDA is a strong bulky base E1OH OTs CI LDA NaOH Br...
4. Predict the products of the following reactions & indicate whether they are most likely to go through an SN2, SN1, E1, or E2 mechanism. NaCN DMSO NaOH CH3OH heat Only one product is formed in the following E2 elimination reaction. Draw an arrow-pushing mechanism for the reaction and provide the correct product structure. Include a 3-D drawing (chair conformation) displaying proper stereochemistry of the transition state to explain formation of only the major product. CH3 •Br NaOCH3 ~"'CHS
Predict the major product or products for the reactions that were involved in several of the experiments this semester (12 pts) 85% 11,PO. heat CH,CH,OH heat S product El prodact COOH saturated NaliCO
predict the major products of the following reactions
Question 5 3 pts Predict the major organic product of the following reactions. Assume one equivalent of reagent unless otherwise stated, it's a solvent, oxidizing, or reducing agent. If no reaction will occur, choose E. Be mindful of stereochemistry ОН Next < Previous
5. (7 pts) Predict the major product(s) for the following reactions. Remember to indicate stereochemistry, when appropriate. If no reaction is expected, write NR. C12 hv а. NBS hv b HBr ROOR с.
Predict the major product(s) or reagent(s) for the following reactions. If more than one product can form, indicate which is the major product. "N(CH2CH) 1) LDA / THE 2) CH CH Be 1) NaOCH-CH, CHỊCH OH 2) CH CHLB 1) NaOCH.CH, CH,CH, OH 2) H0 intramolecular Upload che