
2. Draw the structure of X and complete the following reactions. H2 Lindlar's cat. CH212 CulZn 1. NaNH2 2. CH CH CH...
1. Road-map: NaNH2 1. LDA 2. CH,Br Na/NH 1. O3 2. DMS H2, Lindlar's cat. 1. KMnO4 OH, heat 2. Н,о* 1. OsO4 2. H2S Br2, H2O NaH
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Br Br 1) Excess NaNH2 ? 2) EtC 3) H2, Lindlar's catalyst Draw the expected final product in the box below. Edit 1) NaNH2 2) Mel H CEC H ? 3) 9-BBN 4) H202, NaOH Draw the expected final product in the box below. Edit 1) NaNH2 2) Mel H CE C H 3) NaNH2 4) Et 5) Na, NH3() Draw the expected final product in the box below. ? Edit 1) NaNH2 2) Et H C C...
1. Predict the products of the following reactions. excess NaNH2 THE Br Br H 1. NaNH2 2. CH3CH,Br H2SO4, H20 Hz, Pd/BaSO4 quinoline, CH3OH Na, NH3 1 equivalent HBO NaNH2 Br (excess) 1. Sia,BH, THE 2. H2O2, NaOH HgSO4 H2SO4 H2O
NaNH2 -CH₃ 2) OH CH3CH2Br H3C-EC-H * * CH3CH2CH2Br NaOH, H2O BH/THE H2, Pt CH3Br LI, NH3 (1) NaBH4 OsO4, NaHSO3, H20 Hz, Lindlar's Catalyst In each reaction box, place the best reagent and conditions from the list below. NaNH2 CH3 CH3CH2Br OH H3C-CC-H - - ker CH₂ + HCl CH3CH2CH2Br HO NaOH, H2O BH/THF CH3BT H2, Pt LI, NH3 (1) NaBH4 OsO4, NaHSO3, H20 Hz, Lindlar's Catalyst
1. PREDICT THE PRODUCT: Provide the structure of the major product expected from the following reactions or reaction sequences. Make sure you account for any regio- and/or stereochemistry! (24 pts.) H2O 1. Hg(OAC), CH, OH 2. NaBH H2SO4 H20 1) BH-THF 2) H202, KOH HBr Bry, H2O HBr ROOR 1. BH3-THF 2. H2O2, NaOH H20, H2SO4 1. NaNH2 H2 H-CEC-CH2 CH2 CH3 2. CH CH Br Lindlar cat 1. Sia BH-THF 2. H2O2, H2O
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H2 Lindlar's Catalyst 2. H,02 NaOH 1. BH CH-CHE нс 3. Draw the complete arrow-pushing mechanism for the following reaction. (1.5 pts total) product after step 1 product after step 2 CICI Br- Br 1. Br2 1. C12 show mechanism below show mechanism below
Predict the products of the following reactions. 1 equivalent HBr a. Br NANH2 (excess) Br b. 1. Sia BH, THF 2. H202, NaOH HgSO4 H-SO H2O d.
2. Predict the product(s) to the following reactions, pay attention to stereochemistry: (14pt) 1. NaNH2 3. Hº 1. Oa, -78C 2. H20 H, Pd Baso 1. NaNH2 2. Br. 2 H2 HgSO4 H2SO4 1. Sia BH 2. H2Oz/NaOH
50) 5. Complete the following reactions: 1. LDA a. HC— —c=CH. | 2 CHI bi HC -CECH HO HgSO4 Br. H2O D y Bes: 140 –c =c =CHg. Lindlar H, Pd 1. BH; f HCC-CECH 2. H2O2 HCl 8. Hc ——*-=ch KOH, Alc., Heat KCN HBO
What is the correct sequence of reactions that can achieve the
following multistep transformation?
19:59 TM SM SH REAGENTS A Br B Br HO C H2O HSO4 cat D 1. MCPBA 2.H,0 El. OsO4 2. NaHso F NaNH2 Excess G HO H NBS, hv I HBr ROOR L HBr M NaOtBu N NaOEt O NaOMe P EtOH, H Cat Q Li NH liq RHa Lindlar's S H, Pt TLO 2DMS U1O 2.H20 V Br hv W1. BH,/THF 2NaOH, H20 X1....