Question

Using the label and physician order above, what is the dosage A.J.N. will be receiving every 8 hours of Amikacin in mg and mL?

Case study: A.J.N, age 46, has a wound infection. The culture report stated the infection was caused by Pseudomonas aeruginosa. A.J.N.'s temperature was 104. Amikacin sulfate (Amikin) is to be administered every 8 hours. Dosage is 15 mg/kg daily in three divided doses. A.J.N. weighs 165 pounds. View the Amikacin sulfate (Amikin) Label: Each mL contains 250 ml amikacin USP las the sulfate, 0.66% sodium metabisulfite, 2.5% sodium citrate dihydrate, water for injection qs. air replaced with nitrogen. pH is adjusted with sulfuric acid andlor it necessary sadium tydreaide. pH: 3.5 to 5.5 Sulfate Injection USP Usual Dosage: 15 mekg/day divided equivalent to Amikacin nto 2 or 3 equal doses Do not exceed 1.5 grams daly, See Package Insert for W and other uses. Store at 20 to 25°C(68 to 77 F) See USP Controlled Room Temgeraturel. Teva Pharmaceuticals USA Sellersville, PA 18950 Rev. A 11/2011 500 mg/2 mL 1250 mg/mL) 2 mL Single Dose Vials For IM or lV Use Y10712 10 Vials In preparation for Discussion, consider the following process points before posting to the Discussion Board: Understand when a wound culture should be obtained in order to determine the appropriate antibacterial agent. Think about your rationale On the Discussion Boards, respond to the following: 1. Using the label and physician order above, what is the dosage A.J.N. will be receiving every 8 hours of Amikacin in mg and mL?

Answer 1

1. Using the label and physician order above, what is the dosage A.J.N. will be receiving every 8 hours of Amikacin in mg and mL?

Solution :-

15mg/kg every day in 2– 3 isolated portions (7.5mg/kg at regular intervals or 5mg/kg like clockwork); max 15mg/kg/day. Heavier wt. patients: max 1.5g/day. Regular span: 7– 10 days. Uncomplicated UTIs: 250mg twice every day. Renal weakness: alter portion dependent on serum levels or decrease recurrence; see writing.