Question

Where there patterns to the production and distribution of drugs? Did they resemble each other in how they affected the structures and interactions of producing and consuming areas?

Pomeranz 3.1-3.8 Drugs and World Trade

Answer 1

Production distribution and affects of drug.
TRODUCTION AND DISTRIBUTION OF DRUGS PRODUCTION " Daug production scale Synthers of companies. is the drugs proces of industrial by pharmaceutical I looduction divided - into two parts Scale up Considerations Cooling i Stoichiomeby in Solvent exbaction T BUnit operations ly formulation Powder feeding lilly Milling ing Granulation % Hot melt exlusion SCALE UP CONSIDERATIONS ; COOLING • Viscosity of the reagents increases as the temperatur decreases leading to difficul mering

low temperature results in cresting reagents which will impact the of product of purity 1) Stoichiometry Different stoichiometic satio of regents results in different sation of product formed wi) Solvent Extractions Son formation of emulsions depend upon the solvent UNIT OPERATIONS i Powder feeding Al constant rate are fed into in a constant This proces es the stability constant time raw material and energy the system resulting expaction of output directly depend on of material flow

lowder blending This factor depends on many variables particle size olistribution like particle thape spheres cubes plates Rods irregular I presence of moisture Ly Surface propuses L Paweler flow propesties i) Milling average This postice is done sive in to reduce a drug the powder 1) Granulation small form larg This poshcles particles is poces by which are bound together to known as gronules.

v Hot melt extrusien - This proces involves the application of heat, pressure and agitation to nix materials together and extrude them through a dic The resulting porticles can be blended and compassed into tablets as filled into Capeuls DISTRIBUTION OF ILLEGAL DRUGS These can be distributed by various modes - 11 Illegal distribution network 2) Distribution hierarchy 3) Retail and wholesale market 4) Distributions ties to theft of property 1) Sex work 6) Drug distribution with violence

llegat Distribution Networks Broodly divieled into 4 Categories Upper level distributors Retail selles Wholesale distribut • Responsible Low level distributes holders • Transporters deliveres • mules bolo Dealer financing Smuggling Toonspooting money and Markets Retail Wholesale include Prinats network Public networks a freelance public distribution Prival network These network involve illegal transactions between buyers and sellers. Transactions done by phones, inside homes

aportments, las Thise networks are commonly don Octween com middle class and working consumers. Public Networks This networks involve sellers and lower level distributors & These transaction done in sheets, ports et freelance public distribution In this distributor is responsible for both money and drugs They prefer werk from home Drug distribution with Systemic violence involved among drug distribecien violence conflicts within and groups.

Physical and Social environmental factors Physical factors And pollution proximity to toxic sites Social factors Safety Violence o social disas clu social cohesion Physiological factors ;) Ethnicity and culture in Sexual orientation States and Homelessney 1) Socio economic Ź thnicity and culture Health disposities anse from mony sources including difficulty en accessing offes dable health care , delay in seeking beatment limited socioeconomic recourdes sousim and discrimination