Question

You weigh out 50mg of benzoic acid and dissolve it in 600uL of methylene chloride and then add 600uL of water. Calculate the partition coefficient of this extraction.

Answer 1

The equation to find the partition coefficient is Kp=[(Wmcmg)/(ml of organic solvent)]/[(Wwmg)/(ml of water)

Where Wmc is Weight of Benzoic acid in methylene chloride layer
Where Ww is Weight of Benzoic Acid in Water layer
I used 600 micro litres of Organic Methylene Chloride
I used 600micro liters of Water

For my results I extracted 14mg of Benzoic acid

So, this is how I plugged it in. Kp = [(36mg)/(600micro liter of OL)]/[(14mg)/600 micro liters of water)]

My partition coefficient was Kp = 2.57