The apterous gene in Drosophila encodes a protein required for wing patterning and growth. It is also known to function in nerve development, fertility, and viability. When human and mouse genes whose protein products closely resemble apterous were used to generate transgenic Drosophila (Rincon-Limas et al. 1999. Proc. Nat. Acad. Sci. [USA] 96: 2165–2170), the apterous mutant phenotype was rescued. In addition, the whole-body expression patterns in the transgenic Drosophila were similar to normal apterous.
(a) What is meant by the term rescued in this context?
(b) What do these results indicate about the molecular nature of development?
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