A human female with Turner syndrome (47,X) also expresses the X-linked trait hemophilia, as did her father. Which of her parents underwent nondisjunction during meiosis, giving rise to the gamete responsible for the syndrome?
HINT: This problem involves an understanding of how nondisjunction leads to aneuploidy. The key to its solution is first to review Turner syndrome, discussed above and in more detail in Chapter 7, then to factor in that she expresses hemophilia, and finally, to consider which parent contributed a gamete with an X chromosome that underwent normal meiosis.
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