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Epibatadine, a colorless oil isolated from the skin of the Equadorian poison arrow frog...

Epibatadine, a colorless oil isolated from the skin of the Equadorian poison arrow frog Epipedobates tricolor, has several times the analgesic potency of morphine. It is the first chlorine-containing, non-opioid (nonmorphine-like in structure) analgesic ever isolated from a natural source.

(a) Which of the two nitrogen atoms in epibatadine is the stronger base?

(b) Mark the three stereocenters in this molecule. (Chapter 6)

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Solutions For Problems in Chapter 16

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