Question

Experiment: Reduction of aldehyde or ketone using sodium borohydride as a catalyst and ethanol as the solvent sustem. Add deionized water to the reaction mixture and perform liquid liquid extraction with dichloromethane. Rotovap the organix extract with the dlasj immersed in room temp until no chanfe is observed.

Merowave-Assisted Reduction of Aldehydes or Ketones Post-Lab Questions: 2. Students are asked to "wash their reaction solution, as well as the organic extraction layer. What is/are the most likely impurities that are removed during these washing steps? Provide balanced equation for the overall reaction to help answer this question below. Hint - Track your boron: Balanced Equation: 3. Provide the structure of the unknown ketone/aldehyde starting material that would produce the following HNMR spectrum: Proposed Starting Material: Doublet, 2 Doublet, 2H 7 PPM Page 119

Answer 1

CODECIMON Mechanism of Reeluetion of aldehydes On ketones X4 CONST log in cos tan RR² → R 2 / + Both M+ Na AC a Water work nk HR OH prod R? NaOH)+BH₂

I+I+ Turting water washing step, inorganic impurities like NaoH f BHz dissolves in watch and washed away anced 28th + 3H₂O → 2 H ₃ BO ₃ +3th tions Nach Natfag) + OH(a) Balanced Chemical Bothy dissolves in water to form Boric acid NaOH dissociates into corresponding ione.

a (21) (24) singlet double doublet 8 7 6 5 4 3