
6. Predict the major product for the following reactions. PhCO3H OsO4, H202 H2O, H H20, H Hz. Pt CH=CH2 CH3 dz 02 HO Cola CH3 H2 Pd CH3 HC H с – с KOH H CH3 СНаз, 1. O, CHCI2 2Zn, HOẶC
explain the reaction then make Fischer
projections.
COH 02 syn СОН Ohe ole ole ole Сс Сон сон antt СОН
Answer all parts of the questions
Wower all parts. (a) 1,4-dihydroxynaphthalene can be converted to either the syn stereoisomers as shown below. Each conversion may require more For each conversion give reagents that formed. erica to either the syn-diol or the anti-diol clow. Each conversion may require more than one step. give reagents that may be used and any intermediates 1,4-dihydronaphthalene Syn-diol OH anti-diol HOH (Plus enantiomer) [8 marks] (b) Give a mechanistic explanation for each of the following reactions....
17 Identify the reagent for following conversion H ОН (A) OsO4 (B) KMnO, (C) Na2Cr2O7. H2SO4 (D) N-H CICros (PPC)
Key terms: reactions form predominately or exclusively one enantiomer Enantioselective Sharpless is the addition of a single oxygen atom to an alkene to form an epoxide Reductive of an alkene forms an alkane by addition of H Oxidation Regioselective is the addition of two hydroxy groups to a double forming, a 1,2-diol or glycol Anti Oxidative cleavage of an alkene breaks both the o and n bonds of the double bond to form two carbonyl groups Reduction Dihydroxylation reactions form...
syn o-j-I BHO -H HH CH,CH.CH=CH Syn Arbor Anti? Br 5. Draw the product(s) of the following reaction. (4 pts) В, Draw the mechanism for the above reaction and briefly explain the bond breaking and forming steps (4 pts). (CH3 CH3 Breaks L 6. How many total products, including constitutional isomers and stereoisomers, are possible for th of the following alkyl bromide with ammonia (NH3)? 4 pts (CH3)2CHCHCH.CHCH
What is the product for the following
reaction?
OsO4, NMO acetone, H,0 ОН HO OS ОН НО
10.54 (...) The addition of H-X alkenes has been shown to add predominately via syn-addition, as shown below. н Br H-Br Two chemists disagreed on whether or not syn-addition would happen on terminal alkenes as well. Suggest an experiment through which you could resolve this dispute. H HCI syn or anti? 10.56 (...) When alkynes are treated with water and bromide, a bromoketone is produced. Provide a plausible arrow pushing mechanism, which accounts for the formation of this product. z...
Wame: cold KMnO4, HO-or 1. OsO4 2. NaHSO3 1. mCPBA 2. H+, CH2OH, H2O 1. mCPBA 2. NaOCH3, H2O h.
Identify the missing reagents 1 & 2 draw the final organic product(s) C Reagent 2 Reagent 1 Al NaNH3 1) oso4 2) NaHSO3, H20 CEC Incorrect Periodic acid causes oxidative cleavage of the diol, yielding two carbonyl compounds. HO Reagent 3 HIO4 OH Map dt