Question

1. Intestinal epithelial cells pump glucose into the cell against its concentration gradient using the Na-glucose symporter. Recall that the Na concentration is significantly higher outside the cell than inside the cell. The symporter couples the "downhill" transport of two Na' ions into the cell to the "uphill" transport of glucose into the cell. (opts) a. If the Na concentration outside the cell ([Na Jou) is 161 mM and that inside the cell ([Na'..) is 23.0 mm, and the cell potential is 49.0 mV (inside negative), calculate the maximum energy available for pumping a mole of glucose into the cell. Assume the temperature is 37 °C. Show your work. in AG 712 b. What is the maximum ratio of (glucose) to (glucose]our that could theoretically be produced if the energy coupling were 100% efficient (circle one)? a) 5.2 x 10-4 b) 7.56 c) 1.14 d) 1900

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Answer 1

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chem x 310k xIn22 mM kmoi 8.3143 5015 JImol AG ele (r41 mY) KT X molv 96.5 XLOU0 mol v 4728.5 mol AG cham ele 50IS Timal t+4t28-50/mal) The minimum enegy nuded t pump gluease metraiom gradient is against ln RT Aranspdted Thare art 2 nkt

2x 9743.5 Tms } Calucar 316 kx &31y 3 malk glucore in -7.5 shucoet aut 52x10 3