Question

In your initial post, share your research question/problem from your EBP proposal.

The Evidenced Based Question discusses what the nursing practice has in curbing firearm-based violence before they occur? Discuss the functions of an Institutional Review Board (IRB) and how an IRB supports ethical research.

Answer 1

How to estimate and anticipate a patient's likely course of disease or treatment, excluding intervention factors named in PICO?

As a nurse differentiate the knowledge gap of the problem from the suggested solution of the problem. Precisely describe the gap between present and future expectations. Determining the scope of the problem is important to the EBP process because it helps the team identify important factors influencing and influenced by the problem.  

The mandate of the NIEHS Institutional Review Board (IRB) is to provide ethical and regulatory oversight of research that involves human subjects by:

• Protecting the rights, welfare and well-being of human research participants, recruited to participate in research conducted or supported by NIEHS.
• Ensuring compliance with relevant local, state and federal laws and regulations.
• Ensuring compliance with NIEHS and NIH policies and regulations.
• Employing the highest ethical standards for human research protections in all human subjects research by adhering to the ethical principles outlined in the Belmont report:

Respect for persons

• Persons with diminished autonomy are entitled to protection
• Individuals should be treated as autonomous agents

Beneficence

• Persons are treated in an ethical manner not only by respecting their decisions and protecting them from harm, but also by making efforts to secure their well-being
• (1) Do no harm
• (2) maximize possible benefits and minimize possible harms

Justice

• Fairness in distribution (select participants equitably)
• Who ought to receive the benefits of research and bear its burdens?
• Giving guidance to ensure sound research design, scientific integrity, and determining if the research contributes to generalizable knowledge and is worth exposing subjects to risk.

Independent review by an IRB or equivalent is an important part of a system of protections aiming to ensure that ethical principles are followed and that adequate and appropriate safeguards are in place to protect subjects' rights and welfare while they contribute to ethically and scientifically rigorous research.