Question

4. (4 points) Assign absolute configuration (R or S) to each stereogenic center of the molecules shown below CH ОН ny NH2 OH

Answer 1

(a) So, the absolute R and S configuration with their IUPAC name of the given molecule including their numbering of the group (on the priority basis) and the direction of rotation is given as below:-

(4) As we know that, for assigning the absolute configuration R and S, first we should chose the numbering of the group on the basis of their priority which can be done on the atomic number basis. More atomic number will have the more prior group. Further, if the fourth group in the below the plane and rotation is in clock wise then the configuration will be R and if the fourth group will be on the above plane and rotation is clock wise then the configuration will be S

(3) (2) (R) (1) Он |(R)-2,3-dimethylhexan-3-ol

(b) So, the absolute R and S configuration with their IUPAC name of the given molecule including their numbering of the group (on the priority basis) and the direction of rotation is given as below:-

(4)CH3 (2) (1)(2R) OH Br (3) (3R) CI (1) (2) H2N- (4) CH3 (2R,3R)-3-amino-2-bromo-3-chlorobutan-2-ol

(c) So, the absolute R and S configuration with their IUPAC name of the given molecule including their numbering of the group (on the priority basis) and the direction of rotation is given as below:-

HO (2) H (4) (S) (1) NH2 (3) (S)-2-aminopentanoic acid