Suppose you conduct a case-control study of endometrial cancer, with 200 cases and 200 unmatched controls. According to medical records (which we will assume are correct), 150 of the cases and 100 of the controls have used postmenopausal estrogens.
(a) Construct the appropriate 2x2 table, and compute and interpret the odds ratio for endometrial cancer associated with postmenopausal estrogen use.

Suppose you conduct a case-control study of endometrial cancer, with 200 cases and 200 unmatched controls....
2. In a hypothetical case-control study of 180 cases of heart disease and 300 unmatched controls, the following 2x2 table was determined for the association of sedentary lifestyle with heart disease: Cases Controls Sedentary lifestyle 135 150 Not sedentary lifestyle 45 150 180 300 (a) Compute the odds ratio for sedentary lifestyle and heart disease.
. In a hypothetical case-control study of 180 cases of heart disease and 300 unmatched controls, the following 2x2 table was determined for the association of sedentary lifestyle with heart disease: Cases Controls Sedentary lifestyle 135 150 Not sedentary lifestyle 45 150 180 300 (a) Compute the odds ratio for sedentary lifestyle and heart disease. (b) There is concern that sex may be a confounder in the relationship between sedentary lifestyle and heart disease. What three conditions must...
6. A case-control study of 1700 participants looked at the association between Tamoxifen and uterine cancer. The study included 689 cases. There were 139 cases and 58 controls using Tamoxifen. Fill in the 2x2 table. Calculate and interpret the odds ratio.
Suppose a case-control study asked 238 lung cancer patients and 428 controls (matched to the cases by age and sex) whether they had kept a pet bird during adulthood. Of the 238 lung cancer cases, 99 said yes. Of the 428 controls, 102 said yes. (a) Construct a contingency table for the data. Lung Cancer No Lung Cancer Total Bird No Bird Total (b) Compute the risk (as a %) of lung cancer for bird and non-bird owners for this...
A study looking at ovarian cancer in women compared cases with non-cases, and found that 150/200 cases did not use birth control compared with 50/200 of the non-cases. 1) Create a table to display the data. 2) Calculate the odds of exposure in cases and non-cases. 3) Calculate the odds ratio using the cross-product ratio. 4) How does the difference between the two prevalences of ovarian cancer (75% vs 25%) compare to the odds ratio?
You are given results on a case control study on alcoholism and breast cancer, 200m participants with Breast cancer and 200 participants without cancer were selected and questioned on previous alcohol use. Breast Cancer (+) Breast Cancer (-) Total Heavy alcohol use 40 20 60 No/low alcohol use 160 180 340 total 200 200 400 Calculate and interpret the appropriate measure of association for this study? You later learn that 15 of the controls [Breast CANCER (-)] did not remember...
You are given results on a case control study on alcoholism and breast cancer, 200m participants with Breast cancer and 200 participants without cancer were selected and questioned on previous alcohol use. Breast Cancer (+) Breast Cancer (-) Total Heavy alcohol use 40 20 60 No/low alcohol use 160 180 340 total 200 200 400 Calculate and interpret the appropriate measure of association for this study? You later learn that 15 of the controls [Breast CANCER (-)] did not remember...
Read the following research study and answer the following questions: A case control study was conducted to evaluate the relationship between direct sun exposure and skin cancer. 150 Cases and 100 controls were recruited from Al Wehda hospital. A data collecting method was distributed among both controls and cases. Analysis of data revealed that 70 of cases were exposed to active smoking while only 40 of controls were exposed. Construct a 2 by 2 table to demonstrate the two dichotomous...
Read the following research study and answer the following questions: A case control study was conducted to evaluate the relationship between direct sun exposure and skin cancer. 150 Cases and 100 controls were recruited from Al Wehda hospital. A data collecting method was distributed among both controls and cases. Analysis of data revealed that 70 of cases were exposed to active smoking while only 40 of controls were exposed. Construct a 2 by 2 table to demonstrate the two dichotomous...
A case control-study was conducted looking at maternal exposure to amantadine, a suspected teratogen, and birth defects. The below 2 by 2 shows the data of the study Positive amantadine exposure No amantadine exposure Cases 15 350 Controls 7 950 Calculate the crude Odds Ratio. Does it appear that amantadine is associated with an increased risk of having a child with a birth defect? How would you interpret your Odds Ratio?