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2. Mark is a 30yo businessman who was diagnosed with Crohn’s dz over ten years ago;...

2. Mark is a 30yo businessman who was diagnosed with Crohn’s dz over ten years ago; otherwise, he’s a healthy guy. He’s been free of flare-ups for the past couple of years, but a recent business trip to Thailand (stress, new foods) may have been the trigger for his most recent flare-up, a particularly bad one which put him in your hospital and ultimately resulted in resectioning of his jejunum. Mark was NPO for 3d prior to surgery and 9d post-op; clearly an oversight (oops!) as a result of his being transferred from unit to unit in an effort to clear beds and match changes in staffing patterns as a result of the widespread flu-related shortages. He’s had some D10W here and there, but that’s it.
During your first examination of Mark, you’ve found that he’s developed a fistula in his lower abdomen. It’s determined that the fistula originates in what’s left of his medial jejunum. You discuss the situation with your medical team and it’s decided that Mark should be put on total parenteral nutrition. Your intern has some more questions for you (6pts each):
a. Isn’t TPN expensive, why did we decide to use TPN instead of a tube feed?
b. I heard that peripheral parenteral nutrition provides less risk of infection than a central line. What do you think about placing the catheter so that the formula exits into his median cubital vein?
c. Mark’s been NPO for over 12 days now. I bet he’s really hungry, so I’m going to start him on D30A10 @ 150mL/h. Sound good? Any general suggestions (note: do not need to calculate a new TPN order)?
d. 15 Days Later: This TPN is really working out well. Mark’s fistula is closed, his weight is stable, and all his labs look good. Since he’s doing so well, I think we should just keep him on TPN for another couple of weeks. It’s certainly easier for us than making any changes. What do you think? Why do you think that?
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Answer #1

a.The total parental nutrition is expensive. As the patient has already undergone a surgery in the colon ,the absorption of certain nutrients when given via tube feeding will be interrupted and not absorbed.Further this can increase the workload of the intestine. Normal function of the intestine to return can take some time.In order to prevent the deficiency, malnutrition TPN are more effective because the nutrients can reach the blood strain.Moreover patient is starving or kept NPO for more than seven days will be administered only TPN first.

b.Cebtral line will be the first and priority when trying to administer TPN.The concentration of the solution has a direct impact the blood flow from where it flows. In case a peripheral line is selected there is risk for thrombophlebitis and damage to blood vessels. The median cubital vein can be given the second line of preference beause of its size and diameter compared to other blood vessels to administer TPN.

c..As the patient is more hungry, it means the patient needs calorie to balance it so administration of D30A10 can lead to faster absorption of glucose and calorie production.

d.Tte maximum length of duration for administration of TPN is about 2 weeks or 15 days after surgery.It will not be required more in case when patients are stable and has no malnutrition.It can

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