Question

What are the pathophysiology of Hashimoto Thyroiditis?

Answer 1

Ans: HA SHIMOTO's IROIDITIS PHATHOPHYSI0100ry OF Normal thyroid Activoted helper CCD 4+) Tcells Help B cella produte thyroi d Specific 'auto antibodies. Induce formatiomot CD8 T cells. Antibody dependent cytotozicity Thyroid tell cytotozicity Fas-Fasl mediated Thyroid folulor fo myoj do do tells. DEstruction ofthyroid parenchy malfibrosts & lymphoid intiltrate Hashimoto's Thyroiditis ·

-} pathophy riology of Hashimoto Thyroiditis : * Not mgl, by helper eto44)4 cells thyroid gland is ac tivated * These are, divided into help Bcells to produce thyroid specific and CD 8+ T cells quto antibodies Foumation induce -> Auto anti bodies produce antibo dy de pend ent cytoto xiditeg cytoło xidity -) CD8+ T cells, ag ain divide ce ll Fas - Fas L me dica ted apopto ris of follicular cells! cyto to zicity and Thyrold thyroid combine to destruct -} All these thyroid paren chyma and lymphoid infiltrate . destruction accumulate to Hashimoto Thyroiditig . -> These