Question

Question 5 of 5 1.0 Points When people infected with HIV take the anti-retroviral drug AZT, the viral population evolves to become more and more resistant to AZT. This means the drug becomes less and less effective. However, it is possible that for some HIV patients, the drug may never become less and less effective. That is, some patients taking AZT may not experience a viral population that evolves to become AZT-resistant. Which of the following is the best explanation for the absence of AZT-resistance in some patients? AZT influences the activity of reverse transcriptase, but not other enzymes, so some viral particles still successfully finish their life cycle despite the presence of AZT. Therefore, the evolution of AZT-resistance does not matter. B. When HIV patients take AZT, it affects replication of new HIV particles, and also the patient's cells. The patient may die from side-effects of AZT before the viral particles evolve resistance. Those patients must be from Northern Europe where HIV is not as common among humans, so there is less selection pressure on the viral population for resistance. A mutation resulting in AZT-resistance is a random event. If a relevant mutation conferring resistance never occurs in the viral population, then resistance will not evolve.

Answer 1

Mutation resulting in AZT- resistance is a random event.if a relevant mutation conferring resistance never occurs in the viral population,then resistance will not evolve.