What is the function of the gene product of the H locus ?

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Question

science biology

Answer 1

Answer #1

The gene product of H locus is epistatic to the formation of antigen on the surface of RBC.

A antigen is formed by Ia gene and B antigen is formed by Ib gene. But it HH or Hh is also present, than there is no formation of antigen.

Gene that encodes for H/h is epistatic those that encodes for Ia, Ib and Io.

So, in this case the phenotype and genotype will be as follows -

H_IaIa, H_IaIo, H_IbIb, H_IbIo, H_IaIb, H_IoIo = O blood type

(O blood type have no antigens)

hhIaIa, hhIaIo = A

hhIbIb, hhIbIo = B

hhIoIo = O

hhIaIb = O

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Answer 2

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