Question

low is the drug Neuron neuralgia. This molecule has 2 pKa values associated with it: 3.68 and 10.7 NH3 соо 3a. At what pH would you expect Neurontin to be in the form that is shown? (3 points) 3b. Draw out the molecule as you would expect it to look at the following pH values, note you may need to draw more than one structure to show what this molecule will look like at the given pH values: (4 points each) 3bi. At pH = 1.0: 3bii. At pH 10.7:answer 3B ONLY by using the image on #3 shown

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Answer #1

Isoelectric point is the pH at which the amino acid exists in neutral state(Zwitter ionic form).

Isoelectric point is calculated as mean of both the pK​​​​​a​ of amino acids

PT Pk PK 2 ㄷ 3.68 107 PT PI iso electric N M

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