What type of mutation will result in the production of the regular protein?
neutral
substitution
deletion
frameshift
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What type of mutation will result in the production of the regular protein? neutral substitution deletion...
What type of mutation in HBB produces HgbS? [2 pt] substitution frameshift insertion deletion
Using these types of genetic changes: Base substitution, Transition, Transversion, Missense mutation, Nonsense mutation, Insertion, Deletion, Frameshift mutation Label these genetic changes (a-e). More than one answer may apply to each answer. a. GC->CG in the protein coding region on a gene. b. GC->TA in a GAA glutamate codon c. Loss of three bases GAA for a glutamate codon d. GC->CG in a tRNA gene e. GC->AT in the ribosome binding site of a mRNA
Will an insertion or a deletion of three nucleotides result in a frameshift mutation? Explain why or why not.
11. Match each type of mutation with the corresponding description. (4 points) Missense An insertion or deletion of nucleotides that are not in multiples of 3. Nonsense A mutation that does not alter the protein sequence. Silent A mutation that confers an amino acid substitution. Frameshift A mutation that confers a premature stop codon.
2. If a mutation occurs and alters the sequence CGATATGA to CGATATCA what will be the final effect - compared to the protein that was supposed to be made, how would the actual protein that is synthesized (made) look -shorter, longer or same? 3. Give the sequence of the protein that would result from such a mutation (mutation in question 4. What is the name given to such a mutation? Be specific (answer is not point mutation, deletion, insertion, substitution...
Which type of mutation is likely to be more harmful? Substitution O Frameshift O Silent mutation Missense Point mutation What is the coding portion of a gene called? O Exon O Transcript Intron mRNA Okasaki fragment
Which of the following mutations could result in a truncated protein? Choose all that apply. A missense mutation that changes a phenylalanine to a leucine O A two base pair frameshift O An in-frame removal of three base pairs O A one base pair frameshift A chromosomal-level deletion O o A chromosomal-level insertion O A nonsense mutation that changes a cysteine to a stop codon
QUESTION 20 Which type of mutation is likely to correct (or revert) a transversion mutation? translocation deletion transition transversion frameshift
Why is an insertion or deletion more likely to result in a damaging mutation than a point mutation? 1.Point mutations only change two or three nucleotides 2.Point mutations never change the amino acid that is called for in the protein 3.Insertions/deletions change all codons that follow them, unless they are indels of 3, 6, 9, etc 4.Point mutations cannot result in a stop codon, whereas insertions and deletions can.
A mutation causing an addition or a deletion of one base pair resulted in the production of a nonfunctional mutant protein. The sequences of the normal and mutant proteins are given below. Normal: Met - Leu - Ala - Thr - Gln Mutant: Met - Leu - Ala - His - Pro - Ile - Glu - Ser - Thr - Was this mutation cause by an insertion or a deletion? Answer Below, fill in the codons in the coding...