Question

1. Why is iPS cell therapy using third-party donor cells more feasible than using cells donated from the patient being treated? O Treatment with iPS cells is much more cost prohibitive when iPS cells are donated by the patient being treated. O Donor iPS cells from the patient cannot be used because they contain the disease being treated. O Third-party donor cells are less likely to contain dangerous mutations that can lead to tumor formation. O Third-party donors are screened to ensure they contain forms of genes that will successfully treat the patient's disease. 2. Identify potential benefits of using induced pluripotent stem clls (iPS cells) to treat degenerative diseases. Select the TWO answers that are correct. Because iPS cells are undifferentiated, donor cells from other species are perfect matches to patients, thereby preventing immune rejection. In research, iPS cells can be used td model human biological systems to facilitate discovery of new drug treatments. The use of iPS cells donated by the patient is simultaneously cost effective and carries little or no risk of deleterious mutations. Because iPS cells can become any type of specialized cell, they have potential as regenerative treatments for many different diseases. 3. What are the risks of using induced pluripotent stem cells (iPS cells) to treat degenerative disease? Select the TWO answers that are correct. Using iPS cells to treat some diseases has resulted in resistance to drugs that are important parts of overall treatment regimes There are ethical issues over using iPS cells which are not a concern when using embryonic stem cells. The treatment is cost-prohibitive when iPS cells are derived from samples donated by the patient. Mutations that adversely affect regulation of cell division have been detected in iPS cell lines. .3.0o CLci O4E DM

Answer 1

1. Treatment with iPS cells is much more cost prohibitive when iPS cells are donated by the patient being treated.

2. In research iPS cells can be used to model human biological systems to facilitate discovery of new drug treatments.

Because iPS cells can become any type of specialized cell, they have potential as regenerative treatments for many different diseases.

3. The treatment is cost-prohibitive when iPS cells are derived from samples donated by patients.

Mutations that adversely affect regulation of cell division have been detected in iPS cell lines.