Question

4. Alpha amanitin is found in poisonous mushrooms and irreversibly binds RNA polymerase lI in eukaryotic cells. Why do people die when they eat poisonous mushrooms? (Stating they are poisonous is not an acceptable answer. You need to explain why.] 13 points] 5. Draw a diagram representing the structure of the human DABEARS gene. This gene has 4 exons. The complete precursor mRNA sequence is 2017 bp, [6 pts] a. First draw the gene indicating: promoter sequence, promoter region, enhancer, transcription start site and direction of the gene. Make certain to provide a numbering system. b. Show the precursor mRNA and make certain to label the different structures including exons and introns. Describe and illustrate the processing of the precursor mRNA into the mature mRNA. c.
Please answer 4 and 5?

Answer 1

According to the HOMEWORKLIB RULES I'll answer the first question when more than one question is posted. Do not give thumbs down.

4--)

Alpha amanitin has strong affinity towards the RNA polymerase II. So when we eat the mushroom, the alpha amanitin binds to the RNA polymerase II and cause cytolysis of liver cells. The symptoms are usually don't appear for 2-3 days. Diarrhea and cramps are the first sign of symptoms and after 4-5 day the actual effect on liver and kidney starts and lead to the failure if both kidney and liver and this leads to death of the person.