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Trimethylation of H3K4 generally activates, increasing transcription of the associated gene.
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What does trimethylation of H3K4 generally do to gene expression? Activate, increasing transcription of the associated...
Transcriptional Regulation Gene activation/deactivation 1. what is histone acetylation? How does it affect gene expression? What...
Transcriptional Regulation Gene activation/deactivation 1. what is histone acetylation? How does it affect gene expression? What else can happen to nucleosomes that affects gene expression? Do all the nucleosomes fall off the chromosome at once? 2. what is DNA methylation? How does it affect gene expression? Be able to discuss the examples of DNA methylation covered in class (X inactivation, imprinting). 3. Epigenetics. What is this, and how does it affect gene expression?
Choose the cis-elements. Click on the cis regulatory elements only. Control of eukaryotic gene expression (gene...
Choose the cis-elements. Click on the cis regulatory elements only. Control of eukaryotic gene expression (gene control) can occur at multiple levels from DNA accessibility to post-translational changes to polypeptides/proteins. Silencers, repressors, transcription factors, activators, enhancers, insulators histone acetyltransferases (HATS), histone deacetylases (HDACs) histone remodellers and DNA methyltransferases all play a role in gene control.
Match each term associated with genes and control of gene expression with the appropriate description. A...
Match each term associated with genes and control of gene expression with the appropriate description. A transcriptional unit" that consists of promoter multiple genes under the control of a single regulatory element. A transcriptional regulatory protein (prokaryotic or eukaryotic) which works by turning on or increasing gene transcription. activator The region of a gene to which RNA polymerase binds. Enhancer A transcriptional regulatory protein prokaryotic or eukaryotic) which works by turning off or decreasing gene transcription. repressor A molecule that...
How do transcription factors affect gene expression? a.) They are molecules that can turn genes on...
How do transcription factors affect gene expression? a.) They are molecules that can turn genes on or off. b.) They are mRNAs that contain extra information that is not part of the DNA genome. c.)They modify the chromosome structure to create mutations. d.) They are signals that tell cells whether to divide or not.
what does “coupled” in prokaryotic gene expression mean in transcription and translation. What are two consequnces...
what does “coupled” in prokaryotic gene expression mean in transcription and translation. What are two consequnces for the coupled transcription and translation?
molecular biology 16. Histone acetyltransferases would be directly involved in which of the following? A. Formation of open chromatin B. Movement of the nucleosome C. Acetylation of lysines D. Termin...
molecular biology
16. Histone acetyltransferases would be directly involved in which of the following? A. Formation of open chromatin B. Movement of the nucleosome C. Acetylation of lysines D. Termination of gene expression E. All of the above are true. 17. What functions are accomplished by the primosome? A. Tracking along DNA B. Tracking along DNA, separating double-stranded DNA C. Tracking along DNA, separating double-stranded DNA, synthesizing RNA primers D. Tracking along DNA, separating double-stranded DNA, synthesizing RNA primers, adding...
Two genes (B and C) are transcription factors that affect the expression of gene A. The...
Two genes (B and C) are transcription factors that affect the expression of gene A. The protein product of gene B allows gene A to be transcribed while the protein product of gene C doubles the rate of transcription of gene A. How does the expression of gene A differ between two individuals with the following genotypes? Assume lower case alleles produce non-functional proteins and each gene shows complete dominance. Individual 1: AA : BB : Cc Individual 2: AA...
The hunchback gene has an enhancer containing 3 binding sites for the transcription factor Bicoid. How...
The hunchback gene has an enhancer containing 3 binding sites for the transcription factor Bicoid. How could the loss of a single DNA binding site -leaving the 2 others intact- act to reduce gene expression of hunchback by more than 1/3 ? A. Bound Bicoid transcription factor molecules interact antagonistically to cause maximal gene expression B. Bound Bicoid transcription factor molecules interact additively to cause maximal gene expression C. Bicoid does not bind to the hunchback enhancer D. Bound Bicoid...
Question 3 1 pts What would happen to the expression of this gene if this cell...
Question 3 1 pts What would happen to the expression of this gene if this cell did not have any GAL4 protein and why? It would be always off because GAL4 activates transcription . it would be always on because GAL80 won't be able to bind DNA without GAL4 it would be always on because GAL4 inhibits transcription it would only be on when galactose is present Question 4 1 pts What would happen to the expression of this gene...
Part 1. Eukaryotes use at least two distinct mechanisms to control gene expression by altering the...
Part 1. Eukaryotes use at least two distinct mechanisms to control gene expression by altering the structure of chromatin around a particular gene. One of these mechanisms is the covalent modification of histones to switch DNA between an open and closed confirmation. A second mechanism is the covalent modification of DNA (typically on cytosines) by methylation. A. Describe a type of histone modification and explain what effect is has on chromatin, and how that effect is achieved. a. One type...
Choose the cis-elements. Click on the cis regulatory elements only. Control of eukaryotic gene expression (gene control) can occur at multiple levels from DNA accessibility to post-translational changes to polypeptides/proteins. Silencers, repressors, transcription factors, activators, enhancers, insulators histone acetyltransferases (HATS), histone deacetylases (HDACs) histone remodellers and DNA methyltransferases all play a role in gene control.
Match each term associated with genes and control of gene expression with the appropriate description. A transcriptional unit" that consists of promoter multiple genes under the control of a single regulatory element. A transcriptional regulatory protein (prokaryotic or eukaryotic) which works by turning on or increasing gene transcription. activator The region of a gene to which RNA polymerase binds. Enhancer A transcriptional regulatory protein prokaryotic or eukaryotic) which works by turning off or decreasing gene transcription. repressor A molecule that...
molecular biology
16. Histone acetyltransferases would be directly involved in which of the following? A. Formation of open chromatin B. Movement of the nucleosome C. Acetylation of lysines D. Termination of gene expression E. All of the above are true. 17. What functions are accomplished by the primosome? A. Tracking along DNA B. Tracking along DNA, separating double-stranded DNA C. Tracking along DNA, separating double-stranded DNA, synthesizing RNA primers D. Tracking along DNA, separating double-stranded DNA, synthesizing RNA primers, adding...
Question 3 1 pts What would happen to the expression of this gene if this cell did not have any GAL4 protein and why? It would be always off because GAL4 activates transcription . it would be always on because GAL80 won't be able to bind DNA without GAL4 it would be always on because GAL4 inhibits transcription it would only be on when galactose is present Question 4 1 pts What would happen to the expression of this gene...
Part 1. Eukaryotes use at least two distinct mechanisms to control gene expression by altering the structure of chromatin around a particular gene. One of these mechanisms is the covalent modification of histones to switch DNA between an open and closed confirmation. A second mechanism is the covalent modification of DNA (typically on cytosines) by methylation. A. Describe a type of histone modification and explain what effect is has on chromatin, and how that effect is achieved. a. One type...
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