Question

Question 16 1 pts Most lymphocytes are characterized as taking part in adaptive immunity, but one class of lymphocytes is named "Innate Lymphocyte." Why? Innate lymphocytes require antigen binding to function Innate lymphocytes are active in the skin and mucous membranes Innate lymphocytes don't require antigen binding to function Innate lymphocytes are always active Innate lymphocytes participate in general responses that are the same for every pathogen

Answer 1

Ans - Innate lymphocytes are named so because there function is independent of the antigen binding. (C)  

* They react to tissue perturbations independent of antigen stimulation, and polarization of their effector functions is a feature that largely arises during their development, rather than at the time of immunologic challenge , unlike adaptive T and B lymphocytes.

* Innate Lymphoid Cells (ILCs) lack antigen-specific receptors and do not undergo genomic receptor rearrangements or clonal selection.

* ILCs produce cytokines within hours of activation by tissue damage , in contrast to the days required for naive adaptive lymphocytes .

* Found in peripheral regions of the body such as skin and mucous membranes.